Washington University Digestive Diseases Research Core Center

Core Facilities

The four cores are designed to facilitate analysis of the regulatory factors in the GI tract both in vivo and in vitro and to correlate structure with function. The Administrative Core oversees the operation of the DDRCC and administers the Pilot and Feasibility Program to foster participation by younger, and established, investigators in digestive diseases-related research. In addition, the NIH-sponsored General Clinical Research Center at Washington University provides DDRCC members with resources for conducting clinical research. Several DDRCC members who are experts in translational GI research are utilizing the GCRC.


  • two-dimensional difference gel electrophoresis (2D DIGE)
  • automated image analysis1
  • robotic spot cutting
  • robotic protein digestion
  • protein identification by sensitive high resolution tandem mass spectrometry (MALDI-TOF/TOF and LC-MS/MS)

Visit the Core