Understanding how hepatitis C virus builds its unctuous home.

Publication Type:

Journal Article


Cell host & microbe, Volume 9, Issue 1, p.1-2 (2011)


Hepatitis C virus genome replication occurs in endoplasmic reticulum-derived membrane compartments, but it is unknown how these structures arise. In this issue of Cell Host & Microbe, Reiss and colleagues (2011) show that the virus recruits a specific lipid kinase to replication sites, stimulates its kinase activity, and alters the phospholipid profile of replication compartments.