Center for the Study of Inflammatory Bowel Disease, MGH

Core Facilities

The Biomedical Core program has been a central feature of the CSIBD since its inception. These core resources have been developed to accomplish two goals: first, to support the research activities of the center investigators that increase the understanding of IBD, and second, to stimulate new collaborations and interactions. The biomedical cores have been greatly successful in meeting both of these goals. The first goal has been met through both service and educational activities of the individual cores. As a mark of achieving the second goal, the use of these biomedical cores has led to projects that would not have been undertaken if the cores had not been available. We are continually working to maintain this high level of research support and investigator interaction. The Center has Five cores:


CLINICAL/TISSUE CORE

The Clinical/Tissue Core was developed as a resource for providing carefully collected, catalogued and shared samples from “pedigreed” patients for investigators in this center, thus facilitating the translation of research. These samples include tissue and blood (serum and DNA) from IBD patients and controls. In addition, through the IBD Patient Registry, the core provides ready access to individual patients and populations for basic studies of IBD as well as patients for studies examining disease mechanisms in vivo. An important ancillary role of this core is to create a “gold standard” collection of these materials that serves as a reference standard for scientists nationally. Although the core was not initially conceived to serve as a mechanism to organize clinical therapeutic trials, but to facilitate the study of mechanisms of disease, it has indeed provided an engine for patient-oriented as well as translational IBD research. Learn More...

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