Search the DDRCCs
Enrichment Activities
2012
Intraductal Administration of a Polymeric Nanoparticle Formulation of Curcumin (NanoCurc) Significantly Attenuates Incidence of Mammary Tumors in a Rodent Chemical Carcinogenesis Model Implications for breast cancer chemoprevention in at-risk populations. Chun YS, Bisht S, Chenna V, Pramanik D, Yoshida T, Hong S-M, de Wilde RF, Zhang Z, Huso D, Zhao M, Rudek M, Stearns V, Maitra A, Sukumar S Carcinogenesis, 2012 Jul 25, (2012)
Sialofucosylated Podocalyxin is a Functional E- and L-Selectin Ligand Expressed by Metastatic Pancreatic Cancer Cells. Dallas MR, Chen S-H, Streppel MM, Sharma S, Maitra A, Konstantopoulos K American journal of physiology. Cell physiology, 2012 Jul 18, (2012)
Coordinated effects of microRNA-494 induce G₂/M arrest in human cholangiocarcinoma. Yamanaka S, Campbell NR, An F, Kuo SC, Potter JJ, Mezey E, Maitra A, Selaru FM Cell cycle (Georgetown, Tex.), 2012 Jul 15, Volume 11, Issue 14, p.2729-38, (2012)
Genetically defined subsets of human pancreatic cancer demonstrate unique in vitro chemosensitivity. Cui Y, Brosnan JA, Blackford AL, Sur S, Hruban RH, Kinzler KW, Vogelstein B, Maitra A, Diaz LA, Iacobuzio-Donahue CA, Eshleman JR Clinical cancer research : an official journal of the American Association for Cancer Research, 2012 Jul 2, (2012)
Loss of ATRX or DAXX expression and concomitant acquisition of the alternative lengthening of telomeres phenotype are late events in a small subset of MEN-1 syndrome pancreatic neuroendocrine tumors. de Wilde RF, Heaphy CM, Maitra A, Meeker AK, Edil BH, Wolfgang CL, Ellison TA, Schulick RD, Molenaar QI, Valk GD, Vriens MR, Borel Rinkes IHM, Offerhaus JGA, Hruban RH, Matsukuma KE Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2012 Jul, Volume 25, Issue 7, p.1033-9, (2012)
A composite polymer nanoparticle overcomes multidrug resistance and ameliorates doxorubicin-associated cardiomyopathy. Pramanik D, Campbell NR, Das S, Gupta S, Chenna V, Bisht S, Sysa-Shah P, Bedja D, Karikari C, Steenbergen C, Gabrielson KL, Maitra A, Maitra A Oncotarget, 2012 Jul, Volume 3, Issue 6, p.640-50, (2012)
Mucin 16 (cancer antigen 125) expression in human tissues and cell lines and correlation with clinical outcome in adenocarcinomas of the pancreas, esophagus, stomach, and colon. Streppel MM, Vincent A, Mukherjee R, Campbell NR, Chen S-H, Konstantopoulos K, Goggins MG, Van Seuningen I, Maitra A, Montgomery EA Human pathology, 2012 Apr 26, (2012)
Well-differentiated pancreatic neuroendocrine tumors: from genetics to therapy. de Wilde RF, Edil BH, Hruban RH, Maitra A Nature reviews. Gastroenterology & hepatology, 2012 Apr, Volume 9, Issue 4, p.199-208, (2012)
Loss of expression of the SWI/SNF chromatin remodeling subunit BRG1/SMARCA4 is frequently observed in intraductal papillary mucinous neoplasms of the pancreas. Dal Molin M, Hong S-M, Hebbar S, Sharma R, Scrimieri F, de Wilde RF, Mayo SC, Goggins M, Wolfgang CL, Schulick RD, Lin M-T, Eshleman JR, Hruban RH, Maitra A, Matthaei H Human pathology, 2012 Apr, Volume 43, Issue 4, p.585-91, (2012)
Presence of somatic mutations in most early-stage pancreatic intraepithelial neoplasia. Kanda M, Matthaei H, Wu J, Hong S-M, Yu J, Borges M, Hruban RH, Maitra A, Kinzler K, Vogelstein B, Goggins M Gastroenterology, 2012 Apr, Volume 142, Issue 4, p.730-733.e9, (2012)
Polymeric Nanoparticle-Encapsulated Hedgehog Pathway Inhibitor HPI-1 (NanoHHI) Inhibits Systemic Metastases in an Orthotopic Model of Human Hepatocellular Carcinoma. Xu Y, Chenna V, Hu C, Sun H-X, Khan M, Bai H, Yang X-R, Zhu Q-F, Sun Y-F, Maitra A, Fan J, Anders RA Clinical cancer research : an official journal of the American Association for Cancer Research, 2012 Mar 1, Volume 18, Issue 5, p.1291-302, (2012)
Small cell and large cell neuroendocrine carcinomas of the pancreas are genetically similar and distinct from well-differentiated pancreatic neuroendocrine tumors. Yachida S, Vakiani E, White CM, Zhong Y, Saunders T, Morgan R, de Wilde RF, Maitra A, Hicks J, Demarzo AM, Shi C, Sharma R, Laheru D, Edil BH, Wolfgang CL, et al. The American journal of surgical pathology, 2012 Feb, Volume 36, Issue 2, p.173-84, (2012)
EMT and dissemination precede pancreatic tumor formation. Rhim AD, Mirek ET, Aiello NM, Maitra A, Bailey JM, McAllister F, Reichert M, Beatty GL, Rustgi AK, Vonderheide RH, Leach SD, Stanger BZ Cell, 2012 Jan 20, Volume 148, Issue 1-2, p.349-61, (2012)
Molecular determinants of retinoic acid sensitivity in pancreatic cancer. Gupta S, Pramanik D, Mukherjee R, Campbell NR, Elumalai S, de Wilde RF, Hong S-M, Goggins MG, De Jesus-Acosta A, Laheru D, Maitra A Clinical cancer research : an official journal of the American Association for Cancer Research, 2012 Jan 1, Volume 18, Issue 1, p.280-9, (2012)
Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Jones S, Li M, Parsons WD, Zhang X, Wesseling J, Kristel P, Schmidt MK, Markowitz S, Yan H, Bigner D, Hruban RH, Eshleman JR, Iacobuzio-Donahue CA, Goggins M, Maitra A, et al. Human mutation, 2012 Jan, Volume 33, Issue 1, p.100-3, (2012)
A polymeric nanoparticle encapsulated small-molecule inhibitor of Hedgehog signaling (NanoHHI) bypasses secondary mutational resistance to Smoothened antagonists. Chenna V, Hu C, Pramanik D, Aftab BT, Karikari C, Campbell NR, Hong S-M, Zhao M, Rudek MA, Khan SR, Rudin CM, Maitra A Molecular cancer therapeutics, 2012 Jan, Volume 11, Issue 1, p.165-73, (2012)
2011
Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways. Wu J, Jiao Y, Dal Molin M, Maitra A, de Wilde RF, Wood LD, Eshleman JR, Goggins MG, Wolfgang CL, Canto MI, Schulick RD, Edil BH, Choti MA, Adsay V, Klimstra DS, et al. Proceedings of the National Academy of Sciences of the United States of America, 2011 Dec 27, Volume 108, Issue 52, p.21188-93, (2011)
Presence of pancreatic intraepithelial neoplasia in the pancreatic transection margin does not influence outcome in patients with R0 resected pancreatic cancer. Matthaei H, Hong S-M, Mayo SC, Dal Molin M, Olino K, Venkat R, Goggins M, Herman JM, Edil BH, Wolfgang CL, Cameron JL, Schulick RD, Maitra A, Hruban RH Annals of surgical oncology, 2011 Nov, Volume 18, Issue 12, p.3493-9, (2011)
Cyclin-dependent kinase inhibitor Dinaciclib (SCH727965) inhibits pancreatic cancer growth and progression in murine xenograft models. Feldmann G, Mishra A, Bisht S, Karikari C, Garrido-Laguna I, Rasheed Z, Ottenhof NA, Dadon T, Alvarez H, Fendrich V, Rajeshkumar NV, Matsui W, Brossart P, Hidalgo M, Bannerji R, et al. Cancer biology & therapy, 2011 Oct 1, Volume 12, Issue 7, p.598-609, (2011)
Ectopic overexpression of Sonic Hedgehog (Shh) induces stromal expansion and metaplasia in the adult murine pancreas. Fendrich V, Oh E, Bang S, Karikari C, Ottenhof N, Bisht S, Lauth M, Brossart P, Katsanis N, Maitra A, Feldmann G Neoplasia (New York, N.Y.), 2011 Oct, Volume 13, Issue 10, p.923-30, (2011)
Prevalence of the alternative lengthening of telomeres telomere maintenance mechanism in human cancer subtypes. Heaphy CM, Subhawong AP, Hong S-M, Goggins MG, Montgomery EA, Gabrielson E, Netto GJ, Epstein JI, Lotan TL, Westra WH, Shih I-M, Iacobuzio-Donahue CA, Maitra A, Li QK, Eberhart CG, et al. The American journal of pathology, 2011 Oct, Volume 179, Issue 4, p.1608-15, (2011)
Tumor engraftment in nude mice and enrichment in stroma- related gene pathways predict poor survival and resistance to gemcitabine in patients with pancreatic cancer. Garrido-Laguna I, Uson M, Rajeshkumar NV, Tan AC, de Oliveira E, Karikari C, Villaroel MC, Salomon A, Taylor G, Sharma R, Hruban RH, Maitra A, Laheru D, Rubio-Viqueira B, Jimeno A, et al. Clinical cancer research : an official journal of the American Association for Cancer Research, 2011 Sep 1, Volume 17, Issue 17, p.5793-800, (2011)
A polymeric nanoparticle formulation of curcumin (NanoCurc™) ameliorates CCl4-induced hepatic injury and fibrosis through reduction of pro-inflammatory cytokines and stellate cell activation. Bisht S, Khan MA, Bekhit M, Bai H, Cornish T, Mizuma M, Rudek MA, Zhao M, Maitra A, Ray B, Lahiri D, Maitra A, Anders RA Laboratory investigation; a journal of technical methods and pathology, 2011 Sep, Volume 91, Issue 9, p.1383-95, (2011)
Restitution of tumor suppressor microRNAs using a systemic nanovector inhibits pancreatic cancer growth in mice. Pramanik D, Campbell NR, Karikari C, Chivukula R, Kent OA, Mendell JT, Maitra A Molecular cancer therapeutics, 2011 Aug, Volume 10, Issue 8, p.1470-80, (2011)
Altered telomeres in tumors with ATRX and DAXX mutations. Heaphy CM, de Wilde RF, Jiao Y, Klein AP, Edil BH, Shi C, Bettegowda C, Rodriguez FJ, Eberhart CG, Hebbar S, Offerhaus JG, McLendon R, Rasheed AB, He Y, Yan H, et al. Science (New York, N.Y.), 2011 Jul 22, Volume 333, Issue 6041, p.425, (2011)